Senior Fluidics Engineer

Exthymic
San Diego, CA

We are scientists, engineers, and operators who have spent our careers inside cell therapy manufacturing. We have built the platforms, scaled production, and watched these treatments fail to reach the patients who need them. We are building the technology to close that gap. If this is work you want to do, read on.

About You

You are a hands-on fluidics engineer with a genuine love for making things work at small scales. You move comfortably between CAD and the bench, and you take pride in building systems that are reliable, reproducible, and ready for the next stage of development.

You have direct experience developing and testing fluidic subsystems within life science instruments, from early breadboard concepts through prototyping, integration, and verification. You are self-directed, comfortable with ambiguity, and energized by cross-functional collaboration

  • Own fluidic subsystem design and development - Design, prototype, and iterate on the fluidic architecture of our cell processing platform, including pumps, valves, manifolds, flow cells, and disposable cartridge interfaces, from concept through bench validation.
  • Build and execute test protocols for fluidic performance - Author and run characterization tests covering flow rate accuracy, pressure regulation, dead volume, carryover, and sterility boundary integrity. Own the data, document in design history records, and drive iteration.
  • Collaborate across hardware, biology, and systems teams - Work directly with cell biologists to understand how fluidic conditions affect cell health and process yield, and translate those findings into engineering requirements and design changes.
  • Support instrument integration and system-level testing - Debug fluidic behavior in the context of the full instrument, contribute to integration test execution, and drive failures to resolution.
  • Contribute to design control and documentation - Maintain engineering drawings, BOMs, test reports, and design rationale as living artifacts of the development process.

Requirements

Qualifications

  • Bachelor's or advanced degree in Mechanical Engineering, Biomedical Engineering, Chemical Engineering, or a closely related discipline.
  • Typically at least 4–8 years of hands-on experience designing and testing fluidic systems in an instrument development or life science product context.
  • Proficiency with CAD software (SolidWorks, Onshape, or equivalent) for fluidic component and manifold design.
  • Direct bench experience with pumps, solenoid and proportional valves, pressure sensors, and flow measurement.
  • Experience authoring and executing structured test protocols, capturing data, and writing engineering reports.
  • Comfortable handling primary human cells for functional testing of fluidic subsystems
  • Demonstrated ability to work independently with incomplete requirements and iterate rapidly on physical hardware.

Preferred Qualifications

  • Experience with microfluidic chip design and fabrication.
  • Familiarity with sterile fluid path design, aseptic connections, and biocompatibility requirements for cell-contact materials.
  • Experience designing disposable fluidic consumables, including cartridge interfaces and single-use flow paths.
  • Background working in an early-stage startup or pre-product R&D environment.
  • Exposure to design control processes (DHF, design reviews, FMEA) in a regulated or semi-regulated development context.
  • Familiarity with computational fluid dynamics (CFD) tools for pre-prototyping analysis.
  • Experience in the cell therapy, diagnostics, or genomics instrument space is a plus.
  • Familiarity with AI-assisted design, simulation, documentation, or troubleshooting tools.

Benefits

We offer our employees comprehensive benefits, including medical, vision, and dental coverage, as well as retirement savings plans. Optional benefits include Accident and Term Life offerings.

Agencies

We work directly with candidates and do not accept unsolicited resumes or referrals from recruitment agencies, search firms, or staffing companies. Any resumes submitted by an agency without a signed agreement in place will be considered the property of Exthymic and no fee will be owed. If you are interested in partnering with us on a future search, please contact our HR team directly.

Posted 2026-05-22

Recommended Jobs

Supervising Management Auditor

Department of Resources Recycling & Recovery
Sacramento County, CA

Job Description and Duties Under the general supervision of the Deputy Director, Office of Audits, the incumbent is responsible for planning and organizing the functions of the Office of Audits. Th…

View Details
Posted 2026-05-15

Instructor for Seniors w/ Disabilities Day Program

VistAbility
Concord, CA

Position: Day Program Instructor/Direct Support Professional for Seniors Location: Concord, CA Hours: Monday-Friday: 37.5 hours per week. (CAP) 8:00am-3:30pm  OR (GMC) 8:30am-4:00pm Com…

View Details
Posted 2026-03-28

Investment Real Estate Acquisitions Agent

Kingdom Homes
Los Angeles, CA

About Us: Kingdom Homes is a nationwide real estate wholesaling and flipping company operating in over 15 markets across the U.S. We've transacted on over 500 properties and have made 7 figures…

View Details
Posted 2026-02-04

Global Supply Manager

Amprius Technologies, Inc.
Fremont, CA

About Amprius! Amprius Technologies, Inc. is a leading manufacturer of high-energy, high-power lithium-ion batteries, delivering the industry’s highest commercially available energy density. Headq…

View Details
Posted 2026-03-27

DESIGN INTERNSHIPS: CREATIVE SERVICES DESIGN

California

Welcome to Warner Bros. Discovery… the stuff dreams are made of. Who We Are… When we say, “the stuff dreams are made of,” we’re not just referring to the world of wizards, dragons and superhe…

View Details
Posted 2026-04-21

Customer Service (remote work )

Path Arc
Upland, CA

The customer service representative will be responsible for answering client inquiries, provide product information, and help the customer by being informative, empathetic, and eager to quickly solve…

View Details
Posted 2026-04-28

Project Level Biologist - Natural Resources (On Call - Variable Hours)

SWCA Environmental Consultants
Santa Barbara, CA

About the opportunity: SWCA Environmental Consultants is seeking a Project Level Biologist with experience in natural resource management and biological studies for upcoming environmental projects …

View Details
Posted 2026-01-27

Front Office Overnight Manager - Signia by Hilton San Jose

Hilton
San Jose, CA

The Signia by Hilton San Jose is looking for a Front Office Overnight Manager to join our team!  Our property is across the street from Plaza de César Chávez Park and within walking distance of th…

View Details
Posted 2026-04-27

Facilities Assistant

University of California, Irvine
Irvine, CA

Overview: Founded in 1965, UC Irvine is a member of the prestigious Association of American Universities and is ranked among the nation’s top 10 public universities by U.S. News & World Report. The…

View Details
Posted 2026-05-18

Retail Sales Associate

PUMA Group
Ontario, CA

SPEED & SPIRIT is what we look for in our candidates, defined by some simple values that inspire us to BE DRIVEN in our performance, BE VIBRANT in our sporting legacy, BE TOGETHER in our team spirit,…

View Details
Posted 2026-05-18