Principal Electrical Engineer II

Roche
Santa Clara, CA

: The Position

Roche Sequencing Solutions, Santa Clara, is a fast-moving, highly-technical team with the ambitious goal of disrupting Next-Generation DNA Sequencing. Developing this unique platform requires expertise across a range of fields: FPGA Design, Software Engineering, Data Science, Information Theory, Biophysics, Biology, Chemistry, Circuit Design, and Electrochemistry, among others.

We are looking for an experienced high-speed/mixed signal PCB designer. As a member of our Hardware Control and Compute Development Team, you will have the opportunity to work with experts in each of these fields, focused on the common goal of bringing sequencing-based medical diagnostics instruments to market.

Responsibilities will include:

  • Owning architecture, design, and implementation efforts for instrument electronics and power systems

  • Owning verification and compliance testing efforts for instrument electronics and power systems

  • Designing, manufacturing, and testing high-complexity PCBs and PCBAs

  • Working with other electrical, mechanical, and software engineering teams in system integration

  • Analyzing high-level needs and constraints from stakeholders of multiple disciplines, and deriving system and subsystem requirements and specifications

  • Generating technical documentation, including specifications, technical reports, and procedures

  • Participating in requirements generation and risk/hazard analysis

  • Owning product lifecycle management of electrical and electronics systems

  • Driving development processes within the context of design control SOPs and a QMS

  • Ensuring and promoting best practices for DFM/DFA/DFT/DFS

Minimum Qualifications:

  • M.S. or B.S. degree in EE or related field

  • 10+ years of work experience in an electrical engineering PCB design role

  • Demonstrated success in bringing a product from concept through design and prototyping to production

  • Extensive experience in high-speed (500MHz+ logic, 5GHz+ high-speed serial) mixed-signal PCB and circuit design

  • Extensive experience with PCB/PCBA bring-up, debugging, and testing

  • High proficiency in schematic design and layout, preferably using Altium and Cadence development tools

  • Experience designing under regulatory standards; familiarity with IEC standards a plus

  • Experience and familiarity with power electronics

  • Experience and familiarity with PCB/PCBA designs for complex FPGAs (AMD/Xilinx or Intel/Altera)

  • Good familiarity with industry-standard interfaces and communications protocols/standards (e.g., UART/I2C/SPI/USB, PCIe, 1/10/100G Ethernet, QSFP, DDR3/4, CXL, etc.)

  • Ability to work effectively with minimal supervision in a collaborative environment w/ both onsite and remote colleagues

  • Strong problem-solving skills and ability to track hardware issues to successful resolution

  • Exposure to FPGA digital logic design using Verilog or VHDL; experience a plus

  • Experience with 3D CAD modeling tools a plus

  • Experience with IVD product development a plus

  • Experience using Python, Perl, or similar scripting languages a plus

  • Proficiency with Linux basics a plus

  • Exposure to embedded software development a plus

  • Experience with both designing PCBs from scratch in house and also shepherding designs through an outside service provider as needed by the project.

  • Experience in interfacing with suppliers and manufacturers to anticipate EOL part replacement updates and fast track board manufacturing turnaround time is a plus.

  • Comfortable with converting an existing PCB design from one development tool chain to another (e.g. Allegro to Altium)

  • Experience developing PCBs targeted at Heterogeneous High Performance Computing (HHPC) solutions requiring multiple high speed intra and inter board interfaces (LVDS, QSFP, CXL, PCIe, etc) is a plus

Role is hybrid/onsite in Santa Clara, CA. Relocation benefits are not offered for this role. The expected salary range for this position based on the primary location of Santa Clara is $169,472 and $209,187. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed here: Benefits

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Posted 2026-06-21

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