Clinical Genomics Scientist 2

job summary:

• The Clinical Genomics Scientist 2 serves as a pivotal contributor to a high-throughput, CAP/CLIA-accredited clinical laboratory, focusing on the interpretation of Whole Genome Sequencing (WGS) data. This role is dedicated to resolving the diagnostic odyssey for patients by synthesizing complex genomic data into actionable clinical reports for undiagnosed and cardiovascular disease states. The successful candidate will apply deep scientific rigor to variant triaging and gene curation, ensuring that every result delivered has a direct, quantifiable impact on patient management and clinical outcomes.

location: San Diego, California
job type: Contract
salary: $50.00 - 54.25 per hour
work hours: 9 to 5
education: Masters

responsibilities:

• Execute comprehensive case analysis and interpretation for clinical WGS tests, specifically targeting undiagnosed and cardiovascular disease cohorts.
• Perform systematic medical record review and deep phenotyping to contextualize genomic findings within the patient's clinical presentation.
• Conduct rigorous variant triaging and curation of single nucleotide variants (SNVs), small indels, mitochondrial DNA variants, and copy number variants (CNVs).
• Synthesize complex analytical and clinical characteristics of genetic variants by integrating peer-reviewed literature and bioinformatics data.
• Draft precise, high-quality clinical report language that translates technical genomic findings into clear, diagnostic insights for healthcare providers.
• Collaborate within a multidisciplinary team to refine curation strategies and implement modifications suggested by ClinGen working groups and expert panels.
• Manage a high-volume caseload while maintaining strict adherence to time-sensitive turnaround times and regulatory standards.

qualifications:

Required:

• PhD in Biological Sciences, or a Master's Degree with a minimum of 2 years of direct experience in a clinical laboratory setting.
• Demonstrated proficiency in applying ACMG/AMP guidelines for the interpretation of SNVs, indels, and mitochondrial DNA.
• Technical expertise in applying ACMG/ClinGen standards for the classification and reporting of Copy Number Variants (CNVs).
• Proven ability to evaluate and translate complex scientific literature into clinical evidence for variant classification.
• Mastery of genotype-phenotype relationships and the clinical application of genetic information.
• Exceptional analytical skills with the ability to work under pressure and meet aggressive clinical deadlines.

Preferred:

• Direct experience with ClinGen Sequence Variant Interpretation (SVI) Working Group modifications and Expert Panel guidelines.
• Familiarity with bioinformatics pipelines and statistical approaches to clinical genome analysis.
• Prior experience in a CAP/CLIA-certified environment focused on Rare Disease or Cardiovascular genetics.

#LI-AO1

skills: Genomics, Good Laboratory Practices (GLP), Cardiovascular Diseases, Rare Diseases


Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact [email protected].


Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).


This posting is open for thirty (30) days.

Qualified applicants in San Francisco with criminal histories will be considered for employment in accordance with the San Francisco Fair Chance Ordinance.


Qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.


We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.