Staff Software Engineer

10x Genomics
Pleasanton, CA

10x Genomics makes products that enable researchers to answer biology’s hardest and most elusive questions with single cell and spatial biology technology. Software is at the core of our products, accelerating our customers to insight by enabling them to analyze complex data faster and easier. Scientists have used our tools to discover the mechanisms behind Alzheimer's disease, cystic fibrosis, autism, stem cell differentiation, COVID-19, and more.

As a Staff Software Engineer on the cloud team, you will play a pivotal role in developing cutting-edge, cloud-based applications on AWS that transform how 10x Genomics data is processed, visualized, and analyzed. You will collaborate with computational biologists, scientists, infrastructure teams, other development teams, and our manufacturing teams. The solutions you build will be used globally by thousands of scientists and research labs processing petabytes of genomics data.

What you will be doing


  • Design, build, test, and ship AWS cloud-based solutions.

  • Work with scientists, hardware, product management, design, and other software teams to shape new features and services.

  • Develop scalable systems for efficiently managing petabytes of genomic and image data.

  • Monitor infrastructure and applications for uptime and resource utilization, identify performance bottlenecks, troubleshoot and mitigate system issues, and develop solutions to improve reliability and performance.

Minimum Requirements


  • Bachelor's degree in computer science, engineering, math, or scientific discipline and 4 years of software development OR 6 years of professional experience building software.

  • Experience with backend systems (REST APIs, backend services, relational database systems).

  • Experience with cloud environment and services (e.g. AWS, Kubernetes, Docker, Grafana)

Preferred skills and experience


  • Strong understanding of computer science fundamentals (e.g. data structures, space and time complexity)

  • Deep understanding of testing, continuous integration, deployments and live site monitoring.

  • Experience with Postgres, Go, Typescript.

  • Willingness to solve problems irrespective of where it is in the tech stack.

  • Proficiency in experimenting with and applying new AI technologies in day-to-day work.

  • A background in biology is not required, but curiosity and scientific interest is.

Below is the U.S. base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, experience, and location. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share the specific base pay range for your preferred location and more about the Company’s total compensation package.

Pay Range

$189,100 - $284,500 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Posted 2025-10-01

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