iPSC editing scientist
Description
The Cell Therapy Department is seeking a motivated and detail-oriented Research Associate to join our team. The ideal candidate will contribute to cutting-edge research efforts by performing genomic analyses, NGS molecular profiling, and supporting genome editing projects. This role will interface with a multidisciplinary team of scientists focused on developing innovative therapies and enhancing our understanding of cellular engineering.
- Perform genomics-based experiments, including but not limited to qPCR, ddPCR, NGS amplicon sequencing, RNA-seq, and ATAC-seq to characterize genome engineering method development in iPSCs and T cells.
- Operate, maintain, and troubleshoot laboratory equipment related to genomics workflows, including sequencers and automated liquid handling systems.
- Generate high-quality data by following established protocols, ensuring accuracy, reproducibility, and reliable documentation.
- Maintain organization of samples, reagents, and data in electronic laboratory notebooks (ELNs) and shared databases.
- Analyze and interpret experimental data, summarize findings, and present results to internal stakeholders.
- Proactively engage in troubleshooting experimental issues and contribute innovative ideas for improving workflow efficiency and protocols.
- Role Requirements
- Bachelors (BS) or Masters (MS) degree in Molecular Biology, Genomics, Biotechnology, or a related discipline.
- Demonstrated proficiency in molecular and genomic techniques such as RNA extraction, PCR, qPCR, and NGS library preparation.
- Familiarity with genome editing tools like CRISPR/Cas9.
- Basic understanding of stem cell biology and T cell biology.
- Strong attention to detail, with excellent organizational and communication skills.
- Ability to work both independently and collaboratively in a fast-paced, team-oriented environment.
- Preferred Qualifications
- Experience with ONP sequencing platforms.
- Experience with computational tools for data analysis (e.g., Python/R, IGV, etc.).
- Previous experience in an industrial or biotechnology setting.
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