Sr. Research Associate Discovery Biology
The Opportunity: We are seeking a Senior Research Associate to help the Discovery Biology team advance our discovery and development pipeline. The successful candidate will join a high-functioning team of cell biologists, biochemists, and chemical biologists to help identify new molecules of interest, characterize compounds with novel mechanisms of action, and identify new potential targets. They will contribute to our discovery pipeline from the bench by taking responsibility for developing, optimizing, and troubleshooting new biochemical and cellular assay. The ideal candidate is an open-minded and enthusiastic team player who enjoys problem solving and collaborating cross-functionally to help bring novel therapies to patients. Required Skills, Experience and Education:
BS with 5+ years of experience or MS with 3+ years of experience in Molecular/Cell Biology, Chemical Biology, Biochemistry, Bioengineering, or related discipline.
Proficiency with mammalian cell culture techniques and experience working with diverse cell lines from various tissue and disease backgrounds
Demonstrated proficiency with a wide range of molecular biology and cellular techniques (e.g., Lentiviral Transduction, 2D and 3D cell culture, SDS-PAGE/Western blot, qPCR, CRISPR-based gene editing) and relevant assay technologies (e.g. AlphaLISA/ELISA, high-content microscopy, Luciferase, CellTiter-Glo, TR-FRET/BRET, MSD, flow cytometry)
Experience in microplate-based assay systems, and operation of plate readers or microscopes.
Familiarity with data processing and visualization tools for data analysis (e.g., GraphPad Prism, Genedata Screener, R, etc.).
Knowledge of biochemistry and revlant biochemical techniques is a plus (e.g. protein expression, protein purification, bioconjugation chemistries, SPR, ITC, DSF, FP, etc.)
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