Sr. Product Manager, Health AI

At 23andMe, we're building a new kind of preventative healthcare, powered by a unique dataset that combines deep genetic information with ongoing health data from lab tests, surveys, and EMRs. We’re looking for an AI product leader to architect the intelligence that transforms this rich, multimodal data into a trusted health companion. You will define and build the next generation of AI-powered features that provide continuous, clinician-backed guidance. This is a rare opportunity to shape a product that helps people proactively manage and improve their long-term health.

Who We Are

We are a group of individuals passionate about genetic discovery. 23andMe Research Institute is a nonprofit medical research organization that enables people everywhere to access their genetic information, learn about themselves, and participate in the world's largest crowdsourced research initiative. The Institute aims to be the world's most significant contributor to scientific advancement, uniting people with the common goal of improving health and deepening our understanding of DNA — the code of life.

What You’ll Do

• Own the Feature Roadmap: Own and execute the product roadmap for a core set of new AI-powered health features, from initial concept through launch and iteration.


• Translate Vision into Reality: Specify detailed product requirements for new mobile-first features that use AI to deliver empathetic, trustworthy, and deeply personalized health insights.


• Drive Engagement Loops: Partner with engineering and design to build and optimize features that encourage users to understand their health, take action, and build a lasting relationship with our products.


• Execute with a Cross-Functional Team: Drive feature development by building powerful relationships and seamless processes with R&D, engineering, analytics, design, and marketing.


• Define and Measure Success: Establish and own the key metrics for your features. Analyze user data and product performance to make informed, data-driven decisions for future iterations.


• Be the Voice of the Customer: Collaborate with our consumer insights and product marketing teams to deeply understand user needs, fears, and motivations in the digital health space.

What You’ll Bring

• 5+ years of product management experience with a proven track record of launching successful, consumer-facing web and mobile applications.


• A BS/MS in Computer Science, Engineering, Bioinformatics, Statistics, or a related technical field, or equivalent experience.


• Deep, hands-on understanding of the end-to-end lifecycle of machine learning models, from data collection and feature engineering to model evaluation and deployment.


• Fluency with data analysis; you are comfortable writing your own queries and building dashboards to monitor product health and model performance.


• Excellent communication skills, with the ability to articulate a compelling product vision and navigate complex technical trade-offs with both engineering and executive teams.


• Proficiency in using LLMs in your daily workflow to ideate, iterate, and deliver products more quickly.


• Ability to work from 23andMe's office mid-Peninsula, CA a minimum of 3 days per week

Strongly Preferred

• Direct, hands-on experience building and launching AI/ML-powered products, especially those involving LLMs, NLP, recommendation engines, or predictive modeling.


• Experience building products that leverage large-scale, heterogeneous datasets (e.g., genomic, clinical, behavioral).


• Familiarity with data privacy and security considerations in a regulated environment (e.g., HIPAA).


• Eagerness to collaborate with world-class researchers to build novel products powered by cutting-edge science.

About Us 23andMe, headquartered in California, is a leading consumer genetics and research company. The company’s mission is to help people access, understand, and benefit from the human genome. 23andMe has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world’s largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. 23andMe research participants consent to research conducted by 23andMe which is overseen by an independent third-party Institutional Review Board (IRB) regulated under the 'Common Rule' (45 CFR part 46). More information is available at

At 23andMe, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at [email protected]. 23andMe will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law.

Please note: 23andMe does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you.

Pay Transparency
23andMe takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area. The successful candidate’s starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future.

San Francisco Bay Area Base Pay Range

$175,000—$240,000 USD