Software Engineer III

Heartflow
San Francisco, CA

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFR CT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFR CT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.

Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 400,000 patients worldwide.

We are looking for a Software Engineer III to join our world-class engineering team. In this role, you will help design and develop cloud-based services and modern web applications that power the next generation of Heartflow technologies—including a new orchestration pipeline, which will drive critical workflows across the company.

You will work cross-functionally with Software Engineers, Product Managers, Usability Designers, and Process Engineers to create impactful internal applications and infrastructure. This role offers the opportunity to contribute meaningfully to the design, scalability, and performance of our platforms, while ensuring regulatory compliance in a fast-paced, innovative environment.

Key Responsibilities


  • Design, develop, test, and maintain robust, scalable cloud-based services and APIs.

  • Lead end-to-end feature development across the full technology stack.

  • Write clean, maintainable, well-documented code with a focus on quality, performance, and user experience.

  • Improve infrastructure components including orchestration pipelines, test frameworks, and CI/CD workflows.

  • Contribute to some on-call support and participate in application releases and deployments.

  • Collaborate cross-functionally with Product, Design, and Engineering stakeholders to define and implement product features.

  • Participate in code reviews and champion engineering best practices.

  • Contribute to a culture of technical excellence, innovation, and continuous improvement.

  • Support and mentor junior team members, while working closely with senior engineers on architecture and system design.

  • Ensure compliance with FDA regulations for medical software, including documentation and quality assurance processes.

Required Qualifications


  • Education:


    • BS in Computer Science or a related technical field + 5 years of experience;

    • OR MS/PhD in Computer Science or related field + 3 years;

    • OR equivalent practical experience as a full-stack software engineer.

  • Proficiency in TypeScript or JavaScript .

  • Strong development experience with Python .

  • Cloud development experience (preferably AWS ).

  • Familiarity with modern web frameworks (e.g., Django , Vue.js preferred).

  • Deep understanding of backend and frontend security best practices .

  • Strong problem-solving skills with the ability to analyze and resolve complex issues.

  • Solid grasp of modern software development methodologies including CI/CD , testing , and Agile practices .

  • Excellent communication and collaboration skills.

Preferred Qualifications (How You Stand Out)



  • Advanced proficiency in:


    • Python , Django , JavaScript , TypeScript , Vue.js

    • Nginx , Pytest , GitHub , GitHub Actions

  • Hands-on experience designing and building orchestration pipelines .

  • Strong AWS experience with services such as:


    • CDK , Step Functions , Lambdas , API Gateway , Fargate , ECS , Aurora (MySQL 8.0+)

  • Demonstrated success in delivering cloud-native APIs , scalable web apps, and complex distributed systems.

  • Experience developing regulated medical software (e.g., Software as a Medical Device) in compliance with FDA standards.

Why Join Heartflow?



  • Work on meaningful, life-changing products.

  • Collaborate with top-tier engineers and innovators.

  • Competitive compensation and benefits.

  • Be part of a mission-driven company improving cardiovascular care globally.

If you're passionate about solving complex challenges, innovating in cloud technology, and creating impactful software that improves patient outcomes, we’d love to hear from you.

A reasonable estimate of the base salary compensation range is $160,000 to $200,000 (for San Francisco Bay Area), cash bonus, and equity. #LI-IB1 #LI-Hybrid

Heartflow is an Equal Opportunity Employer. We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination.

Positions posted for Heartflow are not intended for or open to third party recruiters / agencies. Submission of any unsolicited resumes for these positions will be considered to be free referrals.

Heartflow has become aware of a fraud where unknown entities are posing as Heartflow recruiters in an attempt to obtain personal information from individuals as part of our application or job offer process. Before providing any personal information to outside parties, please verify the following: A) all legitimate Heartflow recruiter email addresses end with “@heartflow.com” and B) the position described is found on our careers site at .

Posted 2025-09-22

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