CTM/Clinical Trial Manager

System One
Ontario, CA
Job Title: Clinical Trial Manager
Location: Hybrid, Metro Toronto (Burlington) - 50% per month onsite
Type: 12 months contract
Pay: 50 to 60 per hour CAD


Join a dynamic clinical research team as a Clinical Trial Budgets & Contracts Specialist, where you'll play a key role in managing multi-million-dollar clinical trial budgets and negotiating study contracts that help bring innovative therapies to patients. This hybrid opportunity is ideal for professionals with experience in clinical research, budgeting, and contract management who enjoy collaborating with cross-functional teams in a fast-paced environment.


Accountable for the trial activities for responsible R/ OPU, including but not limited to:
  • Ensure the trial is conducted in compliance with GCPICH, local/global regulations, applicable SOPs and according to the trial protocol by overseeing CRO and internal team activities.
  • Creation, management and review of the R/OPU trial budget to ensure appropriate level of financial oversight and planning accuracy. Timely budget updates based on trial changes.
  • Appropriate trial-specific training of R/OPU internal and external partners is performed in line with Trial Training Plan.
  • Oversees outsourcing of vendor services in the R/OPU in accordance to operating models and governance.
  • Maintains oversight during clinical trial conduct including adherence to GCP and all global and local regulatory requirements; compliance with SOPs and continuous risk monitoring/mitigation. In collaboration with other functions, ensures budget oversight, including support of regular clinical quality monitoring, and safety reporting.
  • Monitor progress of patient recruitment endpoints and proactively update and action contingencies throughout trial conduct.
Minimum Education/Degree Requirements*
Degree /education: Requires a university degree (e.g. Masters degree or comparable degree) with several years relevant experience in required area. Major focus: Biomedical Life Sciences


System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.


System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.


Ref: #568-Clinical

Posted 2026-07-11

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