Accounts Payable (AP) Accountant

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

Summary: Reporting into our Manager of Accounting, as an AP Accountant at Orca Bio, you will take on a strategic and analytical role within the AP function. You will oversee and execute key accounting processes related to accounts payable, ensure accurate recording of liabilities, and support month-end and quarter-end close activities. Your work will help ensure Orca Bio’s financial operations meet both GAAP and SOX compliance standards. You will partner closely with Procurement, FP&A, and external auditors to drive efficiency and accuracy across the AP lifecycle. Success means reconciling complex accounts, ensuring robust documentation, and driving continuous improvement in processes and systems.

• Manage full-cycle accounts payable, including processing vendor invoices in compliance with internal approval workflows and accounting policies
• Support employee expense reimbursement process and enforce T&E policies
• Ensure timely and accurate payments via ACH, check, or wire transfer
• Maintain vendor records and assist with vendor onboarding, including W-9 collection and tax form compliance
• Own the AP-related general ledger reconciliations and prepare journal entries for accruals
• Ensure compliance with internal controls and GAAP for the accounts payables process
• Assist with 1099 reporting and year-end tax filings for vendors
• Support monthly, quarterly, and year-end close processes
• Provide audit support and ensure documentation for AP processes is complete and audit-ready
• Analyze and report on AP metrics and trends, recommending improvements as needed
• Help optimize AP systems and tools for scalability as the company grows

• Bachelor’s degree in Accounting, Finance, or related field required
• 4+ years of accounts payable or general accounting experience required, ideally in a public company or biotech setting
• Solid understanding of GAAP, internal controls, and SOX compliance requirements required
• Proficiency with NetSuite and AP automation tools (e.g., bill.com ) required
• Advanced Excel skills (pivot tables, VLOOKUP, reconciliations) required
• Ability to analyze data, solve problems independently, and propose process improvements required
• CPA eligibility or coursework preferred but not required

$95,000 - $110,000 a year

The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. You will also be eligible to receive pre-IPO equity, in addition to medical, dental, and vision benefits, flexible PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include free daily lunches and snacks at our on-site locations.

Who we are

We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.

We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.

We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.

We maintain a start-up culture of camaraderie and leadership by example, regardless of title.

We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.

Notice to staffing firms

Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.