Lead Full Stack Engineer (NodeJS+React)

Deep Origin
South San Francisco, CA

About Deep Origin

Led by Michael Antonov, a co-founder of Oculus, and well-funded by Formic Ventures, Deep Origin is poised to reinvent the way scientists work and life science innovations come to life. We see a future largely free of diseases, with a 150-year lifespan being the norm. To get there, we are building an operating system for science, enabling scientists to be more productive and to bring tomorrow's ideas to life quickly and at a reasonable cost.

Role Description

We are seeking a talented and experienced Senior/Lead Full Stack Engineer to join our dynamic team. You will be a key member of the software engineering team, building our key functionality and integrating with key partners. You will have ownership in key software feature areas and their architectural design, as well as software implementation with a high level of independence and impact. You will work closely with cross-functional teams to create robust, user-friendly applications that drive the efficiency and effectiveness of biologists and researchers in their scientific endeavors.

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

  • 10+ years of experience designing, building, and operating complex, highly scalable, distributed applications and systems
  • 5+ years of hands-on software development experience with React/TypeScript/JavaScript/NodeJS
  • Experience with both relational databases (e.g., Postgres) and NOSQL (e.g., MongoDB)
  • Knowledge of Kubernetes and Cloud infrastructure/deployment tools (specifically with cluster operations and operators)
  • Has built platforms from an early stage
  • Has scaled platforms to handle many users (10,000+ DAU)
  • Has extensive system-design experience
  • Has experience designing systems with complex datasets/relations
  • Has experience working with distributed systems/platforms
  • Thinks about architecture first and how the code fits in second
  • Has experience working with/implementing a multi-tenant system
  • Systematic problem-solving approach, coupled with a strong sense of ownership and drive
  • Ability to work both independently and on a team
  • Experience working in high-energy startups with fast product delivery mechanisms
  • Must work onsite at least 3 days a week
Posted 2026-02-13

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