Research Associate - Target Discovery

Planet Group
South San Francisco, CA

Research Associate - Target Discovery

We are seeking a highly motivated Research Associate to join our Target Discovery team focused at the interface of immunotherapy and genomics research. This position will work hands-on with primary human tissues and cutting-edge single-cell technologies to support discovery and validation of novel therapeutic targets. The role offers exposure to the full pipeline – from tissue banking and processing to single cell genomics and experimental validation. This is an ideal opportunity for a recent graduate seeking industry research experience in immunology, cancer biology, or single-cell genomics.
Key Responsibilities:
• Coordinate, receive, and bank fresh human tissue samples from CROs and external partners.
• Organize, track, and manage tissue samples stored in LN2, ensuring accurate inventory and documentation.
• Perform dissociation of fresh primary human tissues into single-cell suspensions using
enzymatic and/or mechanical methods.
• Execute single-cell RNA-seq workflows, including cell preparation, FACS, and library
preparation.
• Set up, operate, and maintain flow cytometry instruments and cell sorters.
• Maintain and expand cell lines using sterile cell culture techniques
• Perform target antibody screening workflows using flow cytometry, ELISA, Western blotting, and related methods.
• Analyze and document experimental results; contribute to internal datasets and presentations.
• Collaborate with computational and translational scientists to interpret data and support
identification of candidate therapeutic targets.

Qualifications:
• B.S. or M.S. in biological sciences or a related field (immunology, cancer biology, molecular biology, biochemistry, cell biology, and/or bioengineering).
• Highly organized, detail-oriented, and comfortable managing biological samples and associated metadata
• Hands-on experience with wet-lab techniques, such as mammalian cell culture and sterile technique
• Familiary with primary tissue handling, tissue dissociation, or single-cell workflows is a plus
• Familiarity with FACS and/or flow cytometry
• Strong attention to detail and ability to follow complex protocols
• Ability to work independently while contributing to a collaborative team

What You’ll Gain:
• Direct, hands-on experience with primary human tissues, single-cell genomics, and novel therapeutic target biology
• Exposure to real-world therapeutic target discovery and validation in an industry setting
• Mentorship from experienced scientists and opportunities to present your work
• A front-row seat to how cutting-edge biology translates into drug development

Posted 2026-01-30

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